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Serious adverse events occurred in 8. No consistent pattern of serious adverse events assessed as causally associated with tadalafil administration was observed. None of the four deaths that occurred during the study was assessed as tadalafil related.

There were no clinically significant laboratory or electrocardiographic findings or changes in vital signs in mean baseline-to-endpoint analysis attributable to tadalafil. Tadalafil administration was not causally associated with drug-induced hepatotoxicity, neutropenia, thrombocytopenia, or renal dysfunction. Conclusion: Tadalafil at doses of 5, 10, or 20mg taken as needed up to once daily for 18 to 24 months was safe and well tolerated.

How does Cialis work? Cialis is a phosphodiesterase type 5 PDE5 inhibitor. It works for ED by relaxing smooth muscle in the blood vessels of the penis, therefore increasing blood flow. PDE5 inhibitors only work in the presence of nitric oxide, which is naturally released during sexual arousal.

PDE5 inhibitor medications work in 60 to 70 percent of people with ED. Tadalafil is available in several doses in tablet form: 2. Depending on the dose for ED, you can use it as needed before sexual activity, or take it once a day. But there is a health benefit to taking the least amount of supplements that will do the job.

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Although side effects do still occur, one of the advantages of taking Tadalafil is that it has fewer side effects than other medications used to treat erectile dysfunction.

How do I take Cialis? Taking Cialis hour 10mg , 20mg : You should swallow a Cialis tablet with water about 30 minutes before intercourse. The recommended starting dose for the treatment is 10mg and then adjust as required.

You should not take more than one tablet per day. How to take Cialis daily 2. However, do not take more than one per day. Cialis Daily come in doses of 2. However, for some people, a dose of 2. The tablets can be taken with or without food as it has no effect on the activity of the drug. It should be noted that for the medication to work, you need to be sexually excited as Cialis alone will not result in an erection.

Timescale and effects of Cialis Cialis 10mg and Cialis 20mg act fast; taking effect within 30 minutes. Cialis can last for up to 36 hours in your body while the effects of Cialis Daily are constant in the body.

Cialis Daily is taken every day, so it works continuously. This means you can get an erection at any point during the day upon sexual stimulation. What are the side effects of Cialis? The most common side effects of Cialis are headache, pain in the back, muscle aches and pains, flushing of the face, nasal congestion, indigestion and reflux.

These occur for every 1 in men. How is Cialis different from Viagra? Cialis has the active ingredient Tadalafil, which lasts for as long as 36 hours in the body — perfect for a whole weekend. Also, Cialis takes just 30 minutes to start working while Viagra takes approximately 1 hour before it takes effect.

Cialis vs. Viagra It depends on your circumstances and preferences. Also, each person reacts differently to medication. The most important thing to keep in mind is that Cialis lasts longer and works faster than Viagra. Also, food has an effect on the activity of Viagra but has no effect on Cialis. Why is Cialis cheaper online? Pharmica is a UK registered online pharmacy, specialising in prescription medications. Cialis Tadalafil is available to order online with a free prescription service carried out by UK based and registered pharmacists.

The cheap prices on offer are a result of centralisation. Removing costly high street premises from the pharmacy business model, Pharmica is able to be highly competitive in the marketplace. FAQs skip What is Cialis? Cialis is a brand of medication which contains the active ingredient Tadalafil, which is a treatment for erectile dysfunction. It is available in two variations, Cialis 36 Hour and Cialis Daily, and in four strengths; 2.

The active ingredient Tadalafil is also available at a lower price in a generic version. How long does Cialis last? The effects of Cialis last for up to 36 hours in the body. Cialis reaches peak effectiveness in around 30 minutes. The recommended starting dose for Cialis Daily is 5mg; and for Cialis 36 Hour it is 10mg. When to take Cialis for best results? This gives the medication time to become active in your system. Cialis may remain active in the body for up to 36 hours.

Cialis Daily 2. It's recommended to take the tablet at the same time each day.

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For details about the dosage of Cialis, including its form, strengths, and how to take the drug, keep reading. A skeletal survey or technetium sulfur colloid may be inflamed. Cialis may work to treat ureteral stones by relaxing the ureter muscles.

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Tadalafil is a type of drug used to increase dose flow to the sex organ of males. The Cialis cialis your doctor prescribes will depend on several factors.

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The goal was to have a lower score, which indicates that people have had fewer and less severe symptoms of BPH. The studies looked at people with BPH who took Cialis or a placebo treatment with no active drug. ED is a condition in which a man may have trouble having or maintaining an erection so they can have sex. There are many different causes of ED, including: illness emotional factors, such as stress , depression , or anxiety Sometimes ED can be helped by simply addressing the cause, such as treating an illness or anxiety.

In other cases, you may need medication such as Cialis to treat your ED. Effectiveness Cialis was shown in clinical trials to be an effective medication to treat ED. The people in the study took the survey after 4 weeks. One trial looked at people who took 20 mg of Cialis or a placebo only when needed to treat their ED. This means that their ED symptoms eased while they were taking Cialis. People who took a placebo either lost points or improved by a maximum of only 0. Losing points on the scale means that their ED symptoms worsened.

In another trial , people took 2. In comparison, people who took a placebo had improvements of only 0. In some cases, medications for BPH, such as dutasteride Avodart , may cause a lower libido sex drive and result in ED. The studies used two different questionnaires, one for ED symptoms and one for BPH symptoms, to determine how well the medication worked.

In comparison, people who took a placebo had a decrease in their score of about 3. This means that, on average, people who took Cialis noticed a larger decrease in their BPH symptoms than people who took a placebo. In comparison, people who took a placebo had an increase of only 1. This means that people who took Cialis usually had greater erectile function than people who took a placebo.

Off-label use for Cialis In addition to the uses listed above, Cialis may be used off-label for other purposes. Below is an example of an off-label use for Cialis. However, it may be used off-label for this purpose. The study showed that more people who took Cialis were able to pass their stones than people who took tamsulosin. Ureteral stones usually start out as kidney stones and then move into the ureter the tube that urine travels in from the kidney to the bladder.

Kidney stones are minerals that form a stone inside a kidney. Cialis may work to treat ureteral stones by relaxing the ureter muscles.

This makes the ureter wider, which can help you pass the stones more easily. If you have questions about taking Cialis for ureteral stones, talk with your doctor.

Cialis generic Cialis is available as a generic drug called tadalafil. A generic drug is an exact copy of the active drug in a brand-name medication.

The generic is considered to be as safe and effective as the original drug. Generics tend to cost less than brand-name drugs.

In some cases, the brand-name drug and the generic version may come in different forms and strengths. The Cialis dosage your doctor prescribes will depend on several factors. Your doctor will ultimately prescribe the smallest dosage that provides the desired effect. If you have certain conditions, such as kidney or liver problems, your doctor may have you start with a low dose of Cialis. The following information describes dosages that are commonly used or recommended.

However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs. Drug forms and strengths: 2. Dosage for benign prostatic hyperplasia BPH For symptoms of benign prostatic hyperplasia , the recommended dosage of Cialis is 5 mg once a day.